News - Tosoh launches new column

Da Vinci Laboratory Solutions accelerates growth through acquisition of JSB

Da Vinci Laboratory Solutions and JSB, both value-added resellers of Agilent Technologies and suppliers of high-quality laboratory equipment and services, today announce their merger into a single company as Da Vinci Laboratory Solutions
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Tosoh launches new column

25-02-2019

Tosoh Bioscience GmbH launched a new affinity column - TSKgel FcR-IIIA-NPR - based on a recombinant FcγIIIa receptor ligand. The column is designed for fast assessment for biologic activity of mAbs. The FcγIIIa receptor plays a key role in antibody-dependent cell mediated cytotoxicity (ADCC) by interacting with the N-glycans of the Fc domain of immunoglobulins. Hence, affinity chromatography using immobilized Fc receptor ligands can deliver valuable information about ADCC activity of therapeutic antibodies. As the interaction/affinity is influenced by N-glycans the separation profile also reflect the antibodies glycoform pattern.